Abemaciclib metabolite M20

SKU: orb1309851

Description

Abemaciclib metabolite M20 (CDK4/6-IN-4) is a pharmacologically active and selective CDK4/6 inhibitor derived from Abemaciclib. It is utilized in cancer research to investigate cell cycle inhibition in both in vitro cellular assays and in vivo preclinical models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2138499-06-4
• MW: 522.59
• Purity: 99.29% (May vary between batches)
• Formula: C₂₇H₃₂F₂N₈O
• SMILES: CCN1CCN(Cc2ccc(Nc3ncc(F)c(n3)-c3cc(F)c4nc(CO)n(C(C)C)c4c3)nc2)CC1
• Target: CDK
• Solubility: DMSO:4.5 mg/mL (8.61 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cyclin dependent kinase, CDK4, CDK, CDK4/6-IN-4, CDK6, Abemaciclib metabolite M 20, Abemaciclib metabolite M20, Abemaciclib metabolite M-20, Inhibitor, inhibit, LSN 3106726, LSN-3106726, LSN3106726

Compound Identifiers

PubChem CID

139600311