Abemaciclib metabolite M20

SKU: orb1309851

Description

Abemaciclib metabolite M20 (CDK4/6-IN-4) is a pharmacologically active and selective CDK4/6 inhibitor derived from Abemaciclib. It is utilized in cancer research to investigate cell cycle inhibition in both in vitro cellular assays and in vivo preclinical models.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2138499-06-4
• MW: 522.59
• Purity: 98.10% (May vary between batches)
• Formula: C₂₇H₃₂F₂N₈O
• SMILES: CCN1CCN(Cc2ccc(Nc3ncc(F)c(n3)-c3cc(F)c4nc(CO)n(C(C)C)c4c3)nc2)CC1
• Target: CDK
• Solubility: DMSO:4.5 mg/mL (8.61 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cyclin dependent kinase, CDK4, CDK, CDK4/6-IN-4, CDK6, Abemaciclib metabolite M 20, Abemaciclib metabolite M20, Abemaciclib metabolite M-20, Inhibitor, inhibit, LSN 3106726, LSN-3106726, LSN3106726

Compound Identifiers

PubChem CID

139600311