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A 425619

SKU: orb1219945

Description

A 425619 is a potent TRPV1 antagonistsystemic administration of the TRPV1 antagonist, A-425619, reversed the decrease in digging behavior induced by CFA injection, further confirming the role of TRPV1, expressed by knee neurons, in acute inflammatory joint pain.

Images & Validation

Key Properties

CAS Number581809-67-8
MW345.33
Purity>98% (HPLC)
FormulaC18H14F3N3O
SMILESFC(F)(F)c1ccc(CNC(=O)Nc2cccc3cnccc23)cc1
TargetTRP/TRPV Channel
SolubilityDMSO:34.5 mg/mL (100 mM; Need ultrasonic)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA

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  • A 425619 [orb1298831]

    99.75% (May vary between batches)

    581809-67-8

    345.32

    C18H14F3N3O

    1 mg, 5 mg, 10 mg, 100 mg, 25 mg, 50 mg, 1 ml x 10 mM (in DMSO)
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Protocol Information

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200 mg
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2 mg
$ 320.00
5 mg
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10 mg
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25 mg
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50 mg
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100 mg
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