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7α,25-Dihydroxycholesterol
Catalog Number: orb1707743
| Catalog Number | orb1707743 |
|---|---|
| Category | Small Molecules |
| Description | 7α,25-Dihydroxycholesterol |
| Purity | 98.00% |
| MW | 418.65 |
| Biological Activity | 7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells[1][2], and it is highly potent at activating EBI2 (EC50=140 pM; Kd=450 pM). |
| CAS Number | [64907-22-8] |
| Formula | C27H46O3 |
| SMILES | C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C |
| Storage | -20°C |
| Note | For research use only |
7α,25-Dihydroxycholesterol [orb1219703]
> 98% (HPLC)
64907-22-8
418.7
C27H46O3
10 mg, 25 mg, 50 mg, 1 g, 500 mg, 200 mg, 100 mg
