7α,25-Dihydroxycholesterol

• Catalog Number: orb1219703
• Category: Small Molecules
• Description: 7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells[1][2], and it is highly potent at activating EBI2 (EC50=140 pM; Kd=450 pM).
• Target: Human Endogenous Metabolite|GPR183
• Purity: > 98% (HPLC)
• MW: 418.7
• CAS Number: 64907-22-8
• Formula: C₂₇H₄₆O₃
• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Note: For research use only