7-Chloro-4-(piperazin-1-yl)quinoline

SKU: orb2901873

Description

7-Chloro-4-(piperazin-1-yl)quinolone is an important scaffold in medicinal chemistry. 7-Chloro-4-(piperazin-1-yl)quinolone is apotent sirtuin inhibitor and also inhibits the serotonin uptake (IC50 of 50 μM). 7-Chloro-4-(piperazin-1-yl)quinolone exhibits antimalarial activity on D10 and K1 strains of P. falciparum with IC50s of 1.18 μM and 0.97 μM, respectively.

Key Properties

• CAS Number: 837-52-5
• MW: 247.72
• Purity: >98% (HPLC)
• Formula: C₁₃H₁₄ClN₃
• SMILES: ClC1=CC2=NC=CC(N3CCNCC3)=C2C=C1
• Solubility: In Vitro: DMSO : 50 mg/mL (201.84 mM; Ultrasonic)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only