7-Chloro-4-(piperazin-1-yl)quinoline

SKU: orb1909592

Description

The 7-chloro-4-(piperazin-1-yl)quinolone scaffold is a versatile research compound with dual sirtuin inhibition and serotonin uptake blockade (IC50 50 µM). It also demonstrates potent in vitro antimalarial activity against P. falciparum strains D10 and K1, with IC50 values of 1.18 µM and 0.97 µM, respectively.

Research Area

Epigenetics & Chromatin, Infectious Disease & Virology, Molecular Biology

Key Properties

• CAS Number: 837-52-5
• MW: 247.723
• Purity: 99.72% (May vary between batches)
• Formula: C₁₃H₁₄ClN₃
• SMILES: C1=C(Cl)C=C2C(=C1)C(=CC=N2)N3CCNCC3
• Target: Sirtuin,Others,Parasite

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

738389