3-O-Acetyl-16 alpha-hydroxytrametenolic acid

SKU: orb1220065

Description

3-O-Acetyl-16 alpha-hydroxytrametenolic acid has inhibitory activities against AAPH-induced hemolysis of red blood cells, it shows a strong inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice.In this study, tests were carried out to identify the main ingredient of Hoelen that has the scavenging effect on free-radicals. Triterpene carboxylic acids isolated from the methanol extract of Hoelen, i.e. pachymic acid, polyporenic acid, 3-epidehydrotumulosic acid, 3beta-hydroxylanosta-7,9(11), 24-trien-21-oic acid and 3-O-Acetyl-16 alpha-hydroxytrametenolic acid, were found to have inhibitory activities against AAPH-induced lysis of red blood cells.

Key Properties

• CAS Number: 168293-13-8
• MW: 514.8
• Purity: >98% (HPLC)
• Formula: C₃₂H₅₀O₅
• SMILES: [H][C@]1([C@@H](CCC=C(C)C)C(O)=O)[C@H](O)C[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](OC(C)=O)C(C)(C)[C@]1([H])CC3
• Target: Immunology & Inflammation related
• Solubility: In Vitro: DMSO : 7.14 mg/mL (13.87 mM)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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Gene Symbol

Immunology & Inflammation related