3-O-Acetyl-16α-hydroxytrametenolic acid

SKU: orb1684857

Description

This small molecule exhibits potent anti-inflammatory activity in a murine TPA-induced inflammation model and protects red blood cells from AAPH-induced oxidative hemolysis in vitro. It is a useful research tool for studying oxidative stress and inflammatory pathways.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 168293-13-8
• MW: 514.74
• Purity: 99.75% (May vary between batches)
• Formula: C₃₂H₅₀O₅
• SMILES: [H][C@@]12CCC3=C(CC[C@]4(C)[C@@H]([C@@H](CCC=C(C)C)C(O)=O)[C@H](O)C[C@@]34C)[C@@]1(C)CC[C@H](OC(C)=O)C2(C)C
• Target: Immunology/Inflammation related

Bioactivity

• In Vitro:
  In this study, tests were carried out to identify the main ingredient of Hoelen that has the scavenging effect on free-radicals. Triterpene carboxylic acids isolated from the methanol extract of Hoelen, i.e. pachymic acid, polyporenic acid, 3-epidehydrotumulosic acid, 3beta-hydroxylanosta-7,9(11), 24-trien-21-oic acid and 3-O-Acetyl-16 alpha-hydroxytrametenolic acid, were found to have inhibitory activities against AAPH-induced lysis of red blood cells.

Storage & Handling

• Storage: store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, inhibit, Immunologyrelated, Immunology/Inflammation related, Immunology & Inflammation related, Immunology related, Inflammationrelated, Inflammation related, 3-O-Acetyl-16 a-hydroxytrametenolic acid, 3-O-Acetyl-16 alpha-hydroxytrametenolic acid, 3-O-Acetyl-16 α-hydroxytrametenolic acid, 3-O-Acetyl-16a-hydroxytrametenolic acid, 3-O-Acetyl-16alpha-hydroxytrametenolic acid, 3OAcetyl16αhydroxytrametenolic acid, 3-O-Acetyl-16α-hydroxytrametenolic acid, 3 O Acetyl 16α hydroxytrametenolic acid

Compound Identifiers

PubChem CID

15226712