25-Hydroxycholesterol

SKU: orb1302624

Description

25-Hydroxycholesterol is an oxysterol that regulates cholesterol homeostasis by inhibiting SREBP cleavage and HMG-CoA reductase. It is also a potent and selective suppressor of IgA production in B cells, making it a valuable tool for researching lipid metabolism and B-cell immunology in both in vivo and in vitro models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 2140-46-7
• MW: 402.65
• Purity: 99.89% (May vary between batches)
• Formula: C₂₇H₄₆O₂
• SMILES: C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
• Target: Endogenous Metabolite,HMG-CoA Reductase
• Solubility: Chloroform:50 mg/mL (124.18 mM);Ethanol:20 mg/mL (49.67 mM)

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, HMGCoA Reductase, HMG-CoA Reductase, HMGCoAReductase, EndogenousMetabolite, 25Hydroxycholesterol, 25-Hydroxycholesterol, 25 Hydroxycholesterol, Endogenous Metabolite

Compound Identifiers

PubChem CID

65094