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2-Methyl-5-HT

SKU: orb1940842

Description

2-Methyl-5-HT is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.(In Vivo):2-Methyl-5-HT significantly decreased the time of immobility thus showing anti-depressive-like effects in Male Sprague-Dawley rats.

Images & Validation

Key Properties

CAS Number78263-90-8
MW190.246
Purity>98% (HPLC)
FormulaC11H14N2O
SMILESCc1[nH]c2ccc(O)cc2c1CCN
Target5-HT Receptor
SolubilityIn Vitro: DMSO : 125 mg/mL (657.06 mM)

Bioactivity

In Vivo
2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) significantly decreases time of immobility thus showing anti-depressive-like effects. Animal model: Male Sprague-Dawley rats. Dosage: 3 mg/kg. Administration: i.p.; 45 minutes. Result: Significantly decreased time of immobility thus showing anti-depressive-like effects.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

2-Methyl-5-hydroxytryptamine

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2-Methyl-5-HT (orb1940842)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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5 mg
$ 90.00
10 mg
$ 140.00
25 mg
$ 280.00
50 mg
$ 510.00
100 mg
$ 740.00
500 mg
$ 1,590.00