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2-Fluoroadenine

SKU: orb1306774

Description

2-Fluoroadenine

Research Area

Cell Biology, Molecular Biology

Images & Validation

Key Properties

CAS Number700-49-2
MW153.12
Purity99.49% (May vary between batches)
FormulaC5H4FN5
SMILESNC1=C2NC=NC2=NC(F)=N1
TargetDNA/RNA Synthesis
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (6.53 mM);DMSO:4.4 mg/mL (28.74 mM)

Bioactivity

In Vitro
In Balb-3T3 cells, 2-Fluoroadenine (0.22, 2.2 and 22 μM; 30 hours) inhibits protein, RNA, and DNA syntheses. In CEM cells, 2-Fluoroadenine (2 μM; 4 hours) inhibits CEM cell growth by targeting one or more enzymes involved in either RNA or protein synthesis. In nonproliferating MRC-5 cells, 2-Fluoroadenine (0-1000 μM; 96 hours) exhibits cytotoxicity.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Cytotoxicity, DNA/RNA Synthesis, DNA Synthesis, DNASynthesis, CEM, Anticancer, 2 Fluoroadenine, 2Fluoroadenine, 2-Fluoroadenine, MRC-5, inhibit, NSC 27364, NSC27364, NSC-27364, Inhibitor, RNA Synthesis, RNASynthesis, Purine bases

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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200 mg
$ 70.00
1 ml x 10 mM (in DMSO)
$ 80.00
DispatchUsually dispatched within 5-10 working days
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