2'-Fluoro-2'-Deoxyadenosine

SKU: orb1297913

Description

2'-Fluoro-2'-Deoxyadenosine is a prodrug efficiently converted to the cytotoxic 2-fluoroadenine by E. coli PNP, demonstrating antitumor activity in vivo. It also serves as a building block for synthesizing 2'-fluoro-modified oligonucleotides, which are useful tools for RNA targeting and hybridization studies.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 64183-27-3
• MW: 269.23
• Purity: 99.35% (May vary between batches)
• Formula: C₁₀H₁₂FN₅O₃
• SMILES: Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1F
• Target: Nucleoside Antimetabolite/Analog
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.43 mM);DMSO:50 mg/mL (185.71 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Analog, 2'-Fluoro-2'-Deoxyadenosine, 2'Fluoro2'Deoxyadenosine, 2' Fluoro 2' Deoxyadenosine, oligonucleotide, NucleosideAntimetabolite, Nucleoside Antimetabolite, Nucleoside Antimetabolite/Analog, inhibit, Inhibitor, FAde, purine nucleoside phosphorylase, tumor

Compound Identifiers

PubChem CID

100253