15-LOX-1 inhibitor 1

SKU: orb1693977

Description

9c(i472) is a potent 15-lipoxygenase-1 (15-LO-1) inhibitor (IC50 = 0.19 µM) that suppresses LPS/IFN-γ-induced NF-κB activity, iNOS expression, and lipid peroxidation in macrophage models. This compound is a valuable research tool for studying inflammation, oxidative stress, and related pathways in cellular assays.

Research Area

Metabolism Research, Metabolism Research; Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	2349374-37-2
MW	412.87
Formula	C₂₂H₂₁ClN₂O₄
SMILES	CCOC(=O)c1[nH]c2cc(Cl)ccc2c1\C=C\C(=O)NCc1ccccc1OC
Target	Lipoxygenase,Others

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

145874872 ↗

Key Properties

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No computed properties available.

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