14-Deoxyandrographolide

SKU: orb1299063

Description

14-Deoxyandrographolide, a hepatoprotective diterpenoid from Andrographis paniculata, inhibits TNF-α-induced hepatocyte apoptosis by promoting TNFRSF1A release. This mechanism supports its application in researching liver injury models, both in vitro and in vivo, for studying inflammatory apoptosis pathways.

Research Area

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 4176-97-0
• MW: 334.45
• Purity: 99.98% (May vary between batches)
• Formula: C₂₀H₃₀O₄
• SMILES: [H][C@]12CCC(=C)[C@@H](CCC3=CCOC3=O)[C@]1(C)CC[C@@H](O)[C@@]2(C)CO
• Target: Calcium Channel,Apoptosis
• Solubility: DMSO:3.35 mg/mL (10.02 mM)

Storage & Handling

• Storage: keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

14Deoxyandrographolide, 14-Deoxyandrographolide, 14 Deoxyandrographolide, Apoptosis, Ca channels, Calcium Channel, Ca2+ channels, bovine neutrophils, inhibit, Inhibitor, rat, platelet activating factor, uterine smooth muscle

Compound Identifiers

PubChem CID

11624161