12(S)-HETE

SKU: orb1693213

Description

12(S)-HETE is a bioactive lipid metabolite that stimulates cancer cell proliferation and augments vascular contraction via BLT2 and TP receptor pathways. It is widely used in cardiovascular and oncology research to study oxidative stress and receptor-mediated signaling in both cellular and animal models.

Research Area

Cell Biology, Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 54397-83-0
• MW: 320.47
• Formula: C₂₀H₃₂O₃
• SMILES: C(\[C@H](C/C=C\CCCCC)O)=C/C=C\C/C=C\CCCC(O)=O
• Target: p38 MAPK,DNA/RNA Synthesis,ERK
• Solubility: <0.1 M Na2CO3:2 mg/mL (6.24 mM);Ethanol:1 mg/mL (3.12 mM);PBS (pH 7.2):0.8 mg/mL (2.5 mM);PBS(pH 7.2):< 0.1 mg/mL (insoluble);0.1 M Na2CO3:1 mg/mL (3.12 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DNA/RNA Synthesis, DNA Synthesis, DNASynthesis, 12S-HETE, 12(S) HETE, 12(S)HETE, 12HETE, ERK, RNASynthesis, RNA Synthesis, p38MAPK, p38 MAPK

Compound Identifiers

PubChem CID

5283155