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ZX782

SKU: orb2665328

Description

ZX782 is a small molecule GPX4 degrader that induces ferroptosis by promoting GPX4 destruction via the ubiquitin-proteasome and autophagy-lysosome pathways. This action leads to lethal lipid ROS accumulation in cells like HT1080, making it a valuable tool for studying ferroptosis in cancer research and related in vitro models.

Research Area

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

Key Properties

MW750.28
FormulaC39H48ClN5O8
TargetGlutathione Peroxidase|||Ferroptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Protocol Information