ZWZH-21

SKU: orb3136925

Description

WZH-21 is a selective and orally active dual HDAC1/2 inhibitor, exhibiting an IC50 of 34 nM for HDAC1 and 41 nM for HDAC2. It inhibits the growth of HCT116 and SW480 cells with IC50 values of 0.524 μM and 1.063 μM, respectively. WZH-21 suppresses proliferation and migration of various colorectal cancer cells and induces apoptosis (apoptosis). It is applicable in cancer research, including studies on colorectal cancer.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 3069195-42-9
• MW: 422.48
• Formula: C₂₆H₂₂N₄O₂
• SMILES: O=C(NC=1C=CC=CC1N)C2=CC=C(OCCN3C=4C=NC=CC4C=5C=CC=CC53)C=C2
• Target: HDAC,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

HDAC,Apoptosis