ZW-1226

SKU: orb2664512

Description

ZW-1226 is a potent and selective MRP1 (ABCC1) inhibitor, achieving 65% inhibition of MRP1-mediated transport at 5 µM in a glutathione-dependent manner. It shows high selectivity over P-gp, BCRP, MRP2, and MRP3, making it a valuable chemical probe for investigating multidrug resistance in cancer research, both in vitro and in vivo.

Key Properties

• CAS Number: 2351940-23-1
• MW: 420.42
• Formula: C₂₅H₁₆N₄O₃
• SMILES: N#CC=1C=CC=2C=C3C(=O)NC(=O)N=C3N(C4=CC=C(OCC=5C=CC=CC5)C=C4)C2C1

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

139368918