ZTM000990

SKU: orb2655986

Description

ZTM000990 is a small-molecule antagonist of the oncogenic Tcf4/β-catenin protein complex with IC50 of 0.64 uM; reduces levels of either c-Myc or cyclin D1 in HCT116 cells without effect on cyclin E levels, shows effects on growth of colon and prostate cancer cell lines (IC50=0.15-0.3 uM).

Key Properties

• CAS Number: 115834-23-6
• MW: 697.646
• Purity: >98% (HPLC)
• Formula: C₃₄H₃₅NO₁₅
• SMILES: CC1C(C(C(C(O1)NC2=CC(=O)C3=C(C4=C(C=C3C2=O)C(=O)C5(C6=C(CC(C5(C4=O)OC)O)C=C(C(=C6O)C(=O)OC)C)O)O)OC)O)OC
• Target: Beta-catenin

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SF 2446A1

Quick Database Links

Gene Symbol

Beta-catenin