ZSTK3744

SKU: orb3210733

Description

ZSTK3744 is an aromatic hydrocarbon receptor (AhR) agonist. It directly binds to AhR, enhancing the expression of AhR target genes such as CYP1A1, CYP1B1, and TIPARP, and mediates growth inhibitory activity in triple-negative breast cancer cells. ZSTK3744 induces apoptosis in these cancer cells and exhibits antitumor activity, making it useful for studying chemotherapy-resistant triple-negative breast cancer.

Key Properties

• CAS Number: 3106975-38-3
• MW: 381.43
• Formula: C₂₂H₁₉N₇
• SMILES: N1=CC(=CC2=C1NCC2)C3=NC(=NC4=C3C=CN4C)N5C=NC=6C5=CC=CC6C
• Target: Cytochromes P450,Caspase,Aryl Hydrocarbon Receptor,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Cytochromes P450,Caspase,Aryl Hydrocarbon Receptor,Apoptosis