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ZS3-046

SKU: orb3027884

Description

ZS3-046 is a TAF1 PROTAC degrader that facilitates the ubiquitination and subsequent degradation of TAF1. It can activate p53 and induce apoptosis in acute myeloid leukemia (AML) cells. Additionally, ZS3-046 demonstrates anti-tumor efficacy in AML xenograft mouse models.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

FormulaC49H57N9O7
TargetPROTACs,MDM-2/p53

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information