Zoledronic acid monohydrate

SKU: orb1306411

Description

Zoledronic acid monohydrate (CGP 42446) is a synthetic bisphosphonate that potently inhibits osteoclast-mediated bone resorption. It is widely used in research models of osteoporosis, bone metastasis, and hypercalcemia, with applications in both in vitro cellular assays and in vivo animal studies.

Research Area

Cell Biology, Infectious Disease & Virology

Key Properties

• CAS Number: 165800-06-6
• MW: 290.1
• Purity: 99.91%
• Formula: C₅H₁₂N₂O₈P₂
• SMILES: OC(P(O)(O)=O)(P(O)(O)=O)CN1C=CN=C1.[H]O[H]
• Target: Apoptosis,Autophagy,Antibacterial
• Solubility: 0.1M NaOH:10 mg/mL (34.47 mM);H2O:Insoluble;DMSO:< 1 mg/mL (insoluble or slightly soluble)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, CGP42446, CGP-42446, CGP42446A, CGP 42446, bisphosphonate, anti-cancer, anti-resorptive, Apoptosis, Autophagy, activity, osteoclast, osteoporosis, ZOL 446, ZOL446, ZOL-446, Zoledronic acid, Zoledronic acid Hydrate, Zoledronic acid hydrate, Zoledronic acid monohydrate, Zoledronic acid Monohydrate, zoledronate

Compound Identifiers

PubChem CID

121586