ZN-A-1041

SKU: orb2565014

Description

ZN-A-1041 is a potent small molecule inhibitor, demonstrating high selectivity for HER2 (IC50 = 9.5 nM in BT474 cells) over wt-EGFR (IC50 = 12 µM in H838 cells). This profile supports its use in cancer and inflammation research, including in vitro mechanistic studies and in vivo model investigations.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 2414056-31-6
• MW: 548.54
• Formula: C₂₇H₂₆F₂N₈O₃
• SMILES: O(C=1C=2C(NC3=CC(C)=C(OC4=CC=5N(C=N4)N=CN5)C=C3)=NC=NC2C=CC1OC)[C@H]6C(F)(F)CN(C)CC6
• Target: EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

146448634