ZM223 hydrochloride (2031177-48-5 free base)

SKU: orb1708164

Description

ZM223 hydrochloride is a potent, orally bioavailable, and non-covalent inhibitor of the NEDD8-activating enzyme (NAE). It demonstrates significant anticancer activity in both cellular and animal models, making it a valuable tool for researching NAE biology and oncology.

Research Area

Protein Biochemistry

Key Properties

• MW: 538.99
• Formula: C₂₃H₁₈ClF₃N₄O₂S₂
• SMILES: O=C(C1=CC=C(C(F)(F)F)C=C1)NC2=NC3=CC=C(NC(CSC4=CC=C(N)C=C4)=O)C=C3S2.[H]Cl
• Target: Serine Protease

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

139035004