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ZLDI-8

SKU: orb1308913

Description

ZLDI-8 is a selective ADAM-17 inhibitor that blocks the proteolytic activation of Notch receptors. This small molecule is utilized in vitro and in vivo to investigate the Notch signaling pathway in cancer, inflammation, and cardiovascular research.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number667880-38-8
MW433.523
Purity99.50% (May vary between batches)
FormulaC24H23N3O3S
SMILESCC1=C(\C=C2\C(=O)NC(=S)NC2=O)C2=CC=CC=C2N1CCOC1=C(C)C=C(C)C=C1
TargetGamma-secretase,Phosphatase,Immunology/Inflammation related,Apoptosis,ADAM
SolubilityDMSO: 62.5 mg/mL (144.17 mM), Sonication is recommended.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • ZLDI-8 [orb1219284]

    >98% (HPLC)

    667880-38-8

    433.52

    C24H23N3O3S

    5 mg, 50 mg, 100 mg, 2 mg, 10 mg, 25 mg, 1 g, 500 mg, 200 mg
Quality Guarantee

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Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 100.00
5 mg
$ 170.00
1 ml x 10 mM (in DMSO)
$ 180.00
10 mg
$ 240.00
25 mg
$ 420.00
50 mg
$ 640.00
100 mg
$ 1,000.00
DispatchUsually dispatched within 5-10 working days
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