ZK-Thiazolidinone

SKU: orb1741052

Description

ZK-Thiazolidinone (TAL) is a potent and selective ATP-competitive inhibitor of PLK1 (IC₅₀ = 19 nM). It disrupts mitotic processes like centrosome maturation and spindle assembly in vitro, leading to prometaphase arrest in vivo, and inhibits proliferation in various human and mouse tumor cell lines.

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Key Properties

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CAS Number	891849-87-9
MW	493.55
Formula	C₂₃H₂₆F₃N₅O₂S
SMILES	C(C(NCC(F)(F)F)=O)(C#N)=C1N(CC)C(=O)C(=CNC2=CC(CCN3CCCC3)=CC=C2)S1
Target	Others

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

70918687 ↗

Key Properties

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No computed properties available.

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