ZK 756326

• Catalog Number: orb1304283
• Category: Small Molecules
• Description: ZK 756326
• Purity: 99.06%
• MW: 356.46
• Biological Activity: ZK 756326 is a selective, non-peptide CCR8 chemokine receptor agonist (IC50: 1.8 μM, in human; 2.6 μM, in mouse). Displays no activity at CCR4/5 and CXCR3/4 and shows higher 28-fold selectivity over 26 other GPCRs (less selective at α2A and 5-HT receptors). Induces chemotaxis and inhibits Env-mediated (HIV) cell-cell fusion.
• CAS Number: [874911-96-3]
• Formula: C₂₁H₂₈N₂O₃
• SMILES: Cl.Cl.OCCOCCN1CCN(Cc2cccc(Oc3ccccc3)c2)CC1
• Storage: -20°C
• Note: For research use only