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ZJY-54

SKU: orb3028887

Description

ZJY-54 is an orally active dual inhibitor targeting EGFR/LSD1, with IC50 values of 3.8 nM and 0.6 μM, respectively. It inhibits the proliferation of non-small cell lung cancer cells, induces the accumulation of H3K4me2 and H3K9me2, and suppresses the phosphorylation of EGFR signaling. ZJY-54 exhibits antitumor activity.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction

Images & Validation

Key Properties

TargetHistone Demethylase,EGFR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

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Protocol Information