ZINC194100678

SKU: orb1689743

Description

ZINC194100678 is a potent small-molecule PAK1 inhibitor, exhibiting an IC50 of 8.37 µM. It demonstrates anti-proliferative activity in MDA-MB-231 breast cancer cells with an IC50 of 40.16 µM, supporting its use in cancer research for in vitro mechanistic studies.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1995025-05-2
• MW: 219.24
• Purity: 98.55% (May vary between batches)
• Formula: C₁₀H₁₃N₅O
• SMILES: N(C1=C2C(NN=C2)=NC=N1)C3CCOCC3
• Target: PAK
• Solubility: DMSO:2.2 mg/mL (10.03 mM)

Bioactivity

• Target IC50:
  PAK1:8.37 μM|Antiproliferative:40.16 μM
• In Vitro:
  ZINC194100678, at concentrations ranging from 0-50 μM over 48 hours, exhibits potent antiproliferative effects, as evidenced by an IC50 value of 40.16 μM, in the MDA-MB-231 cell line. This is demonstrated through a cell proliferation assay .
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PAK1

Compound Identifiers

PubChem CID

150720856