Zinc Orotate

SKU: orb1221882

Description

Orotic acid zinc salt dihydrate is an intermediate product in pyrimidine synthesis.

Key Properties

• CAS Number: 68399-76-8
• MW: 411.6
• Purity: >98% (HPLC)
• Formula: C₁₀H₁₀N₄O₁₀Zn
• SMILES: c1c([nH]c(=O)[nH]c1=O)C(=O)[O-].[Zn+2].c1c([nH]c(=O)[nH]c1=O)C(=O)[O-]
• Target: Wnt/beta/catenin

Bioactivity

• In Vivo:
  Orotic acid is a marker for measurement of urea cycle disorders (UCDs), including ornithine transcarbamylase deficiency (OTCD). Orotic acid (1.0% addition to the diet; p.o. for 3-10 d) induces a development of fatty liver by day 7, and decreases purine/pyrimidine ratio of hepatic acid-soluble nucleotides by day 3.
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• In Vitro:
  Orotic acid is found in milk and dairy products, and it is converted to uridine for use in the pyrimidine salvage pathway predominantly in liver, kidney and erythrocytes.
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Wnt/beta/catenin