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ZINC-1000507824

SKU: orb3210582

Description

ZINC-1000507824 is a non-covalent, reversible inhibitor of the RNA cytosine-5 methyltransferase NSUN2. It targets the SAM cofactor binding pocket of NSUN2, forming a stable NSUN2-ligand complex. ZINC-1000507824 destabilizes oncogenic mRNAs encoding components of the PI3K/AKT and MAPK/ERK pathways, reducing growth signaling and proliferative drive, and restoring therapeutic sensitivity in cancer cells. This compound is applicable in research focused on NSUN2-driven malignancies.

Images & Validation

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ZINC-1000507824

Key Properties

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TargetPI3K,DNA Methyltransferase,Akt,p38 MAPK,ERK

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Quick Database Links

Gene Symbol
PI3K,DNA Methyltransferase,Akt,p38 MAPK,ERK

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