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ZIKV-IN-6
Catalog Number: orb1944034
| Catalog Number | orb1944034 |
|---|---|
| Category | Small Molecules |
| Description | ZIKV-IN-6 (compound 22) is a direct inhibitor of the Zika virus (ZIKV) that binds to its RNA-dependent RNA polymerase (RdRp), obstructing viral RNA synthesis mediated by the ZIKV NS5 protein. The compound exhibits low cytotoxicity (CC50 > 50 μM) and mitigates excessive inflammatory response and pyroptosis [1]. |
| Purity | 98.00% |
| Biological Activity | ZIKV-IN-6 (compound 22) acts as a direct inhibitor of the Zika virus (ZIKV) by binding to its RNA-dependent RNA polymerase (RdRp) and obstructing viral RNA synthesis mediated by the ZIKV NS5 protein. This compound also demonstrates low cytotoxicity (CC50 > 50 μM) and mitigates the excessive inflammatory response and pyroptosis [1]. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
