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Catalog Number | orb1744545 |
---|---|
Category | Small Molecules |
Description | Zidesamtinib (NVL-520) is an orally active, selective, potent, and blood-brain-barrier-crossing inhibitor of ROS1 fusion and resistance mutations, inhibits ROS1 and ROS1 G2032R, and can be used in the study of non-small-cell lung cancer and solid tumors. |
Purity | 99.78% |
MW | 419.455 |
Biological Activity | Zidesamtinib (NVL-520) is an orally active, selective, potent, and blood-brain-barrier-crossing inhibitor of ROS1 fusion and resistance mutations, inhibits ROS1 and ROS1 G2032R, and can be used in the study of non-small-cell lung cancer and solid tumors. |
CAS Number | 2739829-00-4 |
Formula | C22H22FN7O |
SMILES | C(C)N1C2=C(CC=3C(C=4C([C@@H](C)OC=5C=C2C=NC5N)=CC(F)=CC4)=NN(C)N3)C=N1 |
Storage | -20°C |
Note | For research use only |