Zidesamtinib

• Catalog Number: orb1744545
• Category: Small Molecules
• Description: Zidesamtinib (NVL-520) is an orally active, selective, potent, and blood-brain-barrier-crossing inhibitor of ROS1 fusion and resistance mutations, inhibits ROS1 and ROS1 G2032R, and can be used in the study of non-small-cell lung cancer and solid tumors.
• Purity: 99.78%
• MW: 419.455
• Biological Activity: Zidesamtinib (NVL-520) is an orally active, selective, potent, and blood-brain-barrier-crossing inhibitor of ROS1 fusion and resistance mutations, inhibits ROS1 and ROS1 G2032R, and can be used in the study of non-small-cell lung cancer and solid tumors.
• CAS Number: 2739829-00-4
• Formula: C₂₂H₂₂FN₇O
• SMILES: C(C)N1C2=C(CC=3C(C=4C([C@@H](C)OC=5C=C2C=NC5N)=CC(F)=CC4)=NN(C)N3)C=N1
• Storage: -20°C
• Note: For research use only