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ZDZ-553

SKU: orb3211030

Description

ZDZ-553 is an orally active STAT1 inhibitor with an IC50 value of 0.87 μM. It modulates the STAT1 signaling pathway, influencing downstream lipid metabolism and inflammatory pathways. In mouse models of non-alcoholic steatohepatitis (NASH), ZDZ-553 reduces liver steatosis and decreases inflammatory responses. ZDZ-553 also has distinct safety features and is suitable for research related to NASH.

Images & Validation

Key Properties

TargetSTAT

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information