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ZD-1-186

SKU: orb3177253

Description

ZD-1-186 is a non-degradable molecular glue that effectively inhibits MYC expression in diffuse large B-cell lymphoma cells and significantly induces the expression of CDKN1A (p21). This compound facilitates the binding of BCL6 to BRD9, a non-canonical BAF complex bromodomain protein involved in sustaining MYC transcriptional activity in certain lymphoma contexts. ZD-1-186 is applicable for research in targeted transcriptional reprogramming.

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Key Properties

Targetc-Myc,Molecular Glues

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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ZD-1-186 (orb3177253)

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