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ZBP1/RIP3/MLKL activator 1

SKU: orb3134535

Description

ZBP1/RIP3/MLKL activator 1 (compound 3a) is a synthesized quinoline derivative that can induce DNA damage, elevate intracellular reactive oxygen species (ROS) levels, and trigger apoptosis through the caspase pathway. Furthermore, when apoptosis is inhibited, it facilitates necroptosis via the ZBP1-RIP3-MLKL pathway. This compound is useful in cancer research, particularly for targeting cells with impaired apoptotic mechanisms.

Research Area

Infectious Disease & Virology

Images & Validation

Key Properties

FormulaC26H28N6O2
TargetMLK,Necroptosis,RIP kinase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

ZBP1/RIP3/MLKL activator 1 (orb3134535)

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