ZBP1/RIP3/MLKL activator 1

SKU: orb3134535

Description

ZBP1/RIP3/MLKL activator 1 (compound 3a) is a synthesized quinoline derivative that can induce DNA damage, elevate intracellular reactive oxygen species (ROS) levels, and trigger apoptosis through the caspase pathway. Furthermore, when apoptosis is inhibited, it facilitates necroptosis via the ZBP1-RIP3-MLKL pathway. This compound is useful in cancer research, particularly for targeting cells with impaired apoptotic mechanisms.

Research Area

Cell Biology, Infectious Disease & Virology, Signal Transduction

Key Properties

• Formula: C₂₆H₂₈N₆O₂
• Target: Necroptosis,RIP kinase,MLK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Necroptosis,RIP kinase,MLK