ZAP-180013

SKU: orb1298704

Description

ZAP-180013 is a small molecule inhibitor targeting ZAP70 with an IC50 of 1.8 µM. It serves as a valuable research tool for investigating T-cell receptor signaling in both cellular and biochemical assays, aiding the study of immune cell activation and related pathologies.

Research Area

Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 873080-25-2
• MW: 454.33
• Purity: 98.89% (May vary between batches)
• Formula: C₁₉H₁₇Cl₂N₃O₄S
• SMILES: CCS(=O)(=O)c1ncc(Cl)c(n1)C(=O)N(Cc1ccco1)Cc1ccc(Cl)cc1
• Target: Tyrosinase,Tyrosine Kinases
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (11.01 mM);DMSO:250 mg/mL (550.26 mM)

Bioactivity

• Target IC50:
  ZAP70:1.8 μM (IC50)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Tyrosinase, tyrosine, Tyrosine Kinases, TyrosineKinases, ZAP70, ZAP-70, ZAP-180013, ZAP180013, ZAP 180013, T-cell, antigen, autoimmune, Inhibitor, inhibit

Compound Identifiers

PubChem CID

2988718