Zaltoprofen sulfoxide

SKU: orb3174987

Description

Zaltoprofensulfoxide (Compound M2) is the primary metabolite of Zaltoprofen. It is a potent and selective COX-2 inhibitor (IC50 = 45.38 nM) and also acts as a PPAR-γ activator. Zaltoprofen sulfoxide effectively suppresses NF-κB and MAPK inflammatory signaling pathways, alleviating LPS-induced acute lung injury. This compound is valuable for studying acute lung injury.

Research Area

Immunology & Inflammation, Metabolism Research, Molecular Biology, Neuroscience, Signal Transduction

Key Properties

• CAS Number: 134085-79-3
• MW: 314.36
• Formula: C₁₇H₁₄O₄S
• SMILES: O=C(O)C(C1=CC=C2C(=C1)CC(=O)C=3C=CC=CC3S2=O)C
• Target: PPAR,Drug Metabolite,COX,p38 MAPK,NF-κB

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PPAR,Drug Metabolite,COX,p38 MAPK,NF-κB