Z57346765 hydrochloride

SKU: orb3027392

Description

Z57346765 hydrochloride is an inhibitor of phosphoglycerate kinase 1 (PGK1) that binds to the ADP binding site, with a K\(_D\) value of 2.09 × 10⁻⁵ M, thereby reducing the metabolic enzyme activity of PGK1, glucose consumption, and lactate production. Additionally, it inhibits DNA replication, impairs DNA damage repair, and induces cell cycle arrest in renal clear cell carcinoma (KIRC) cells.

Key Properties

• MW: 330.81
• Formula: C₁₇H₁₉ClN₄O
• SMILES: OCCNC1=NC(NC2=CC=C(C)C=C2)=NC3=CC=CC=C31.Cl
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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