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Z1609609733

SKU: orb3135286

Description

Z1609609733 (Compound 18) is a non-covalent inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 1.46 μM. It effectively suppresses serine synthesis, interferes with cancer metabolism, and completely halts cell proliferation.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number2375374-15-3
MW596.46
FormulaC30H27Cl2N3O6
SMILESO=C(OC(OC(=O)C(C=1C=NC=CC1)C2=CC=C(C=C2)C3(NC(=O)C4=CC=5C(Cl)=C(Cl)C=CC5N4C)COC3)C)C
TargetDehydrogenase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information