(Z)-Nexinhib20

SKU: orb1944715

Description

Nexinhib20 is a small molecule inhibitor that disrupts Rab27a-JFC1 interactions and Rac1-GTP activity, suppressing neutrophil exocytosis and inflammation. Its research applications include studies on systemic inflammation and myocardial ischemia-reperfusion injury, with utility in both in vitro and in vivo experimental models.

Key Properties

• CAS Number: 1162656-24-7
• MW: 300.31
• Purity: 99.98% (May vary between batches)
• Formula: C₁₅H₁₆N₄O₃
• SMILES: C(\C(C(C)(C)C)=O)(=C/C1=CC(N(=O)=O)=CC=C1)/N2C=NC=N2
• Target: Others
• Solubility: DMSO:45 mg/mL (149.85 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Nexinhib20, (Z)4,4dimethyl1(3nitrophenyl)2(1,2,4triazol1yl)pent1en3one

Compound Identifiers

PubChem CID

5715188