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Z-LLF-CHO

SKU: orb1944494

Description

Z-LLF-CHO is a potent inhibitor of the chymotrypsin-like activity of the proteasome (Ki=460 nM) and also blocks NF-κB nuclear translocation. This cell-permeable aldehyde is used in vitro to study proteasome function, NF-κB signaling pathways, and associated cellular processes like inflammation and apoptosis.

Research Area

Protein Biochemistry

Images & Validation

Key Properties

TargetProteasome
CAS Number133429-58-0
MW509.64
FormulaC29H39N3O5
SMILES[C@@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)CC(C)C)=O)(C(N[C@@H](CC2=CC=CC=C2)C=O)=O)CC(C)C

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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