(Z)-Capsaicin

SKU: orb1309743

Description

Zucapsaicin is the synthetic cis-isomer of natural capsaicin, developed for the treatment of osteoarthritis-associated knee pain and neuropathic pain. Its mechanism, targeting the TRPV1 receptor, has been investigated in both in vitro assays and in vivo models of inflammatory and neuropathic pain.

Research Area

Infectious Disease & Virology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 25775-90-0
• MW: 305.41
• Purity: 99.67% (May vary between batches)
• Formula: C₁₈H₂₇NO₃
• SMILES: COC1=C(O)C=CC(CNC(=O)CCCC\C=C/C(C)C)=C1
• Target: HSV,TRP/TRPV Channel
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.55 mM);DMSO:60 mg/mL (196.46 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, hTRPV1, HSV, Herpes simplex virus, (Z) Capsaicin, (Z)Capsaicin, (Z)-Capsaicin, Capsaicin, Civamide, cis-Capsaicin, Zucapsaicin, TRPVChannel, TRPV Channel, TRP Channel, TRPChannel, Transient receptor potential channels

Compound Identifiers

PubChem CID

1548942