(Z)-4EGI-1

SKU: orb1693165

Description

(Z)-4EGI-1 is a cell-permeable inhibitor that disrupts the eIF4E/eIF4G interaction, thereby suppressing cap-dependent translation initiation with an IC50 of 43.5 μM. This compound exhibits anticancer properties and is used in research to study oncogenesis and protein synthesis inhibition in both cellular and animal models.

Research Area

Cell Biology

Key Properties

• CAS Number: 901787-88-0
• MW: 451.28
• Formula: C₁₈H₁₂Cl₂N₄O₄S
• SMILES: N(/N=C(/CC1=C(N(=O)=O)C=CC=C1)\C(O)=O)C2=NC(=CS2)C3=CC(Cl)=C(Cl)C=C3
• Target: PERK,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

6911989