YX0798

SKU: orb3028039

Description

YX0798 is a selective, orally active CDK9 inhibitor (Kd: 0.28 nM). It downregulates the oncogenic protein c-MYC and the pro-survival protein MCL-1. YX0798 disrupts the cell cycle and causes transcriptome reprogramming, ultimately leading to apoptosis. The compound exhibits antitumor activity.

Research Area

Cell Biology

Key Properties

• MW: 465.86
• Formula: C₂₁H₁₉ClF₃N₅O₂
• SMILES: ClC(C=NC(NC([C@H]1CCC[C@@H](NC(C(F)(F)F)=O)C1)=O)=C2)=C2C3=C4C(NC=C4)=NC=C3
• Target: Bcl-2 Family,c-Myc,CDK,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Bcl-2 Family,c-Myc,CDK,Apoptosis