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Description

YVPGP is an oligopeptide extracted from Anthopleura anjunae. It exhibits significant anti-tumor activity by mediating the PI3K/AKT/mTOR signaling pathway. YVPGP can arrest DU-145 cells in the S phase and induce apoptosis (apoptosis) through mitochondrial and death receptor pathways (caspase3, 7, 8, 9). It effectively inhibits tumor growth in a DU-145 xenograft mouse model, showing potential for prostate cancer research.

Research Area

Cell Biology, Protein Biochemistry, Signal Transduction

Images & Validation

Key Properties

TargetBcl-2 Family,Akt,mTOR,PI3K,Apoptosis,Caspase
CAS Number2095286-57-8
MW531.60
FormulaC26H37N5O7
SMILESC([C@@H](NC([C@H](CC1=CC=C(O)C=C1)N)=O)[C@H](C)C)(=O)N2[C@H](C(NCC(=O)N3[C@H](C(O)=O)CCC3)=O)CCC2

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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