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Catalog Number | orb1298541 |
---|---|
Category | Small Molecules |
Description | YUM70 |
Purity | 98.01% |
MW | 398.84 |
Biological Activity | YUM70 is a potent and selective glucose-regulated protein 78 (GRP78) inhibitor(with an IC50 of 1.5 μM for inhibiting GRP78 ATPase activity of the full-length protein). It induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer. |
CAS Number | [423145-35-1] |
Formula | C21H19ClN2O4 |
SMILES | CCCC(=O)NC(c1ccc2OCOc2c1)c1cc(Cl)c2cccnc2c1O |
Storage | -20°C |
Note | For research use only |