YS-67

SKU: orb2281168

Description

YS-67 is a potent, selective, and orally bioavailable EGFR inhibitor. It demonstrates antitumor activity by suppressing p-EGFR and p-AKT, inhibiting proliferation and inducing G0/G1 phase cell cycle arrest and apoptosis in cells like A549, PC-9, and A431, supporting its research use in non-small-cell lung cancer.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2761327-15-3
• MW: 522.64
• Purity: 98.88%
• Formula: C₃₂H₃₄N₄O₃
• SMILES: N=1C=NC(=C2C=C(OCCCN3CCOCC3)C(OC)=CC12)C=4C=5C=CC=CC5N(C4C=6C=CC=CC6)CC
• Target: Apoptosis,Akt,EGFR
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.91 mM);DMSO:10 mg/mL (19.13 mM)

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

YS67, EGFR, Apoptosis, Akt

Compound Identifiers

PubChem CID

164628028