YLT-11

SKU: orb1744142

Description

YLT-11 is a highly selective and orally bioavailable PLK4 inhibitor with a Kd of 5.2 nM, demonstrating potent antiproliferative effects. It induces G2/M arrest and apoptosis in vitro and has shown efficacy in in vivo xenograft models, supporting its use in cancer research, particularly for studying centrosome amplification and tumorigenesis.

Research Area

Cell Biology

Key Properties

• MW: 412.49
• Formula: C₂₄H₂₄N₆O
• SMILES: CC(=O)NC1=NC=CC(=N1)C2=CC3=C(C=C2)C(=NN3)/C=C/C4=CC=C(C=C4)CN(C)C
• Target: Apoptosis,Others,PLK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

134821508