YL5084

SKU: orb1982560

Description

YL5084 is a covalent inhibitor with high selectivity for JNK2 (IC50 = 70 nM) and JNK3 (IC50 = 84 nM) over JNK1. It exhibits antiproliferative and pro-apoptotic activities in cellular models, which are reported to be independent of its JNK2 inhibitory function, making it a useful research tool for studying JNK isoform-specific signaling.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2440199-73-3
• MW: 600.71
• Formula: C₃₅H₃₆N₈O₂
• SMILES: N(C=1N=C(C=2C(=NN3C2C=CC=C3)C4=CC=CC=C4)C=CN1)[C@@H]5CN(C(=O)C6=CC=C(NC(/C=C/CN(C)C)=O)C=C6)C[C@@H]5C
• Target: JNK,Others,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

153610906